PRIMATE SCIENCE RESEARCH HIGHLIGHT Jan. 14, 1999 "Fish oils have many neurological benefits" (Article text reprinted with permission from the Oregon Regional Primate Research Center) Fish oils-what are they good for? Lots, according to a recent news program of National Public Radio that featured the Center's Martha Neuringer, Ph.D. Dr. Neuringer spoke about the importance of omega-3 fatty acids, which are found in high concentrations in mothers' breast milk, for the development of the eyesight and brain function in monkey and human infants. Based on Dr. Neuringer's work, omega-3s were increased in infant formulas several years ago. However, better forms of omega-3s, more like those in breast milk, are now being tested. The Food and Drug Administration has not yet approved the addition of these new sources to infant formulas in this country. Dr. Neuringer explained that it is important to continue evaluating the benefits and the safety of particular forms of omega-3 fatty acid supplementation. Other researchers working with human infants have established the role of omega-3 fatty acids in infant brain development. From such research, scientists went on to find that fish oil diet additives reduced the incidence of schizophrenic and manic depressive episodes in adult psychiatric patients. Scientists think that there may be a link between the fact that depression has been on a steady increase in the U.S. population during this century, and the fact that at the same time the food sources of omega-3 fatty acids-fish oil, canola oil and leafy green vegetables-have all but disappeared from many peoples' meals. It may be that a deficit of these fatty acids, which are stored in the membranes of neurons, interferes with communication between brain cells. ### References: Reisbick S., M. Neuringer , E. Gohl, R. Wald, and G.J. Anderson. 1997. Visual attention in infant monkeys: Effects of dietary fatty acids and age. Dev Psychol. May;33(3):387-95. Neuringer M. 1996. Assessment of retinal function and vision in infants. In: Assessment of Infant Visual and Cognitive Function in Relation to Long Chain Polyunsaturated Fatty Acids (S.E. Carlson, M. Neuringer, and S. Reisbick). Basel: Editiones Roche. pp. 19-48. Neuringer M. 1999. Infant vision and retinal function in studies of dietary long-chain polyunsaturated fatty acids: Methods, results and implications. Am J Clin Nutr (in press). **************************** Primate-Science Research Highlights appears every other week and focuses broadly on research involving non-human primates. Coverage includes biomedicine, behavior, conservation and veterinary science. Please submit highlights for this column to Larry Jacobsen, Primate-Science Research Highlights editor, at jacobsen@primate.wisc.edu. A 300-word limit and lay-language style are recommended. Primate-Science Research Highlights are supported by a grant from the National Institutes of Health, National Center for Research Resources. Copyright 1999, Wisconsin Regional Primate Research Center. No portion of this highlight may be copied or redistributed without the consent of the editor. ****************************