IMMUNOLOGY A Short Course FOURTH EDITION Eli Benjamini Professor Emeritus Department of Medical Microbiology and Immunology University of California School of Medicine Davis, California Richard Coico Professor and Chairman Department of Microbiology and Immunology City University of New York Medical School New York, New York Geoffrey Sunshine Staff Scientist Health Effects Institute Cambridge, Massachusetts and Lecturer. Department of Pathology Tufts University School of Medicine Boston, Massachusetts Wiley-Liss A John Wiley & Sons, Inc., Publication 2000 CONTENTS-Chapter Titles 1. Introduction and Overview 1 2. Elements of Innate and Acquired Immunity 17 3. Immunogens and Antigens 41 4. Antibody Structure and Function 57 5. Antigen-Antibody Interactions, Immune Assays, and Experimental Systems 87 6. The Genetic Basis of Antibody Structure 117 7. Biology of the B Lymphocyte 135 8. The Role of the Major Histocompatibility Complex in the Immune Response 147 9. Biology of the T Lymphocyte 169 10. Activation and Function of T and B Cells 187 11. Control Mechanisms in the Immune Response 211 12. Cytokines 229 13. Complement 253 14. Hypersensitivity Reactions: Antibody-Mediated (Type 1) Reactions 279 15. Hypersensitivity Reactions: Antibody-Mediated (Type 2) Cytotoxic Reactions and Immune Complex (Type 3) Reactions 301 16. Hypersensitivity Reactions: T-Cell Mediated, Type 5-Delayed-Type Hypersensitivity 317 17. Autoimmunity 329 18. Immunodeficiency and Other Disorders of the Immune System 347 19. Transplantation Immunology 379 20. Tumor Immunology 401 21. Resistance and Immunization to Infectious Diseases 421 Glossary 455 Appendix 477 Index 481 From the Back Cover: The Fourth Edition of Immunology: A Short Course, completely updated on a chapter-by-chapter basis, contains extensive revisions to reflect the many recent advances in our understanding of immunology. This text contains a thorough introduction to immunology and concludes each chapter with review questions. Among the numerous additional features are clinical case scenarios and new, full-color illustrations that have been specially designed for this edition. Within this edition, particular emphasis is placed on T-and B-cell responses to antigen, antigen processing and presentation, vaccination technology, immunotherapy, and mechanisms responsible for immune disorders. Immunology: A Short Course, Fourth Edition proves itself to be an invaluable tool by offering the most coherent presentation of topics available. Included in the fully revised new edition: -Two new chapters on cytokines and immune responses to infection - Updated case scenarios and review questions - Accompanying Web site with downloadable illustrations and up-to-date CD and cytokine tables www.wiley.com/benjamini - Full-color interior with all new figures Immunology: A Short Course, Fourth Edition is the clear choice when searching for a concise and accessible book in modern immunology. WHERE TO ORDER: John Wiley & Sons, Inc. 1 Wiley Dr. Somerset, NJ, 08875-1272 U.S.A. Phone: 800-225-5945 Fax: 732-302-2300 COST: Paper $48.50 (ISBN: 0471348902)
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