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University of Wisconsin–Madison
Wisconsin National Primate Research Center
A legacy of life-saving research and humane animal care

Virology Services

Virology Services staff member Andrea Weiler operates the LC-96 instrument.

The WNPRC Virology Services Unit provides expert support to investigators performing virological research in nonhuman primates. Our services include highly sensitive molecular diagnostics, production and titration of virus stocks suitable for in-vitro and/or in-vivo studies, generation of custom virus mutants by reverse genetics, virus isolation and more.

Our clients include investigators studying the nonhuman primate AIDS viruses simian immunodeficiency virus (SIV) and simian-human immunodeficiency virus (SHIV), influenza, Zika virus and dengue, among other viruses.

Services Supported

  • Detection of viral RNA by ultrasensitive quantitative RT-PCR (QRT-PCR). Viral targets include
    • SIV/SHIV
    • Simultaneous quantification of wild-type SIV and nef deletion mutants
    • Influenza viruses
    • Zika virus
    • Dengue virus
    • Yellow fever virus 17D
    • Simian arteriviruses
  • Production of characterized virus stocks:
  • Production of custom SIV mutants
  • Isolation of nonhuman primate viruses in tissue culture
  • Assays to measure the latent reservoir of SIV:
    • Quantitative viral outgrowth assay (download our QVOA white paper.pdf)
    • Quantification of cell-associated SIV DNA by QPCR

To request service, please contact Virology Services Unit Head Thomas Friedrich, Ph.D. or virologyservices@lists.wisc.edu.

Pricing Information

Virology Services pricing

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